The global agreement had specific requirements to fund an anti-smoking information campaign, tobacco-related medical research and a large number of other anti-smoking cessation and prevention programmes. The MSA, with the exception of the creation of the American Legacy Foundation, had no obligation for states to use the money they received for tobacco control purposes (Table 4 ▶). The various colonies of Mississippi and Minnesota have also established private foundations dedicated to tobacco control;1 the aggregate allocations to these foundations are lower than what the overall regulation would have provided for similar functions. While tobacco control advocates were free to compete with some of that money in state legislation for tobacco control, only six states have spent the minimum resources recommended by the Centers for Disease Control and Prevention on a vast tobacco control effort9,27 A large area of „loss“ since the global agreement has been the inability to reach FDA jurisdiction over tobacco products. While there is a general consensus that the global comparison has created serious procedural problems for the FDA to actually act in this jurisdiction1, many of these issues have been resolved in the bill based on the global comparison sponsored by Senator McCain.